{"id":503,"date":"2025-09-28T07:24:26","date_gmt":"2025-09-28T07:24:26","guid":{"rendered":"https:\/\/birdstesting.com\/?p=503"},"modified":"2025-11-25T02:01:34","modified_gmt":"2025-11-25T02:01:34","slug":"%d0%b3%d0%b5%d0%bd-drd4-7r-%d1%83-%d0%b3%d0%be%d0%bb%d1%83%d0%b1%d0%b5%d0%b9","status":"publish","type":"post","link":"https:\/\/birdstesting.com\/ru\/%d0%b3%d0%b5%d0%bd-drd4-7r-%d1%83-%d0%b3%d0%be%d0%bb%d1%83%d0%b1%d0%b5%d0%b9\/","title":{"rendered":"\u0413\u0435\u043d DRD4 \u0443 \u0441\u043a\u0430\u043a\u043e\u0432\u044b\u0445 \u0433\u043e\u043b\u0443\u0431\u0435\u0439: \u041f\u043e\u0447\u0435\u043c\u0443 \u043e\u043d \u0432\u0430\u0436\u0435\u043d \u0438 \u043a\u0430\u043a \u0435\u0433\u043e \u043f\u0440\u043e\u0432\u0435\u0440\u0438\u0442\u044c"},"content":{"rendered":"<p>DRD4 Gene Test: Homing Motivation, Alertness &amp; Core Three Indicators | SENO<\/p>\n<h3>Disclaimer<\/h3>\n<p data-path-to-node=\"4\">The <a href=\"https:\/\/birdstesting.com\/bird-dna-testing-kits-for-sale\/\" data-internallinksmanager029f6b8e52c=\"2\" title=\"kit\">Racing Pigeon<\/a> Performance DNA Test provided by our laboratory is intended solely for research, breeding reference, and academic purposes. The test results should not be regarded as a decisive predictor of racing performance, nor should they be used as a factor for qualifying, ranking, or evaluating pigeons in any official racing events. Actual racing outcomes are influenced by multiple environmental and management factors; therefore, the genetic findings serve only as limited reference information. Our laboratory makes no guarantees or commitments regarding the application of these results to real-world racing performance.<\/p>\n<h2>1. What Is the DRD4 Gene and Why Is It Crucial for Racing Pigeons?<\/h2>\n<p data-path-to-node=\"6\">The DRD4 gene encodes the dopamine D4 receptor, a protein that transmits dopamine signals in the brain. Dopamine influences a pigeon&#8217;s attention, exploratory behavior, stress response, and learning capacity.<\/p>\n<p data-path-to-node=\"7\">The DRD4 gene is recognized by our laboratory and clients as one of the <b>Core Three Indicators<\/b> (DRD4, CRY1, LDHA). It does not affect physique or stamina directly, but it determines <b>homing motivation, alertness, exploration drive, and stress tolerance.<\/b> These mental and behavioral factors translate directly into homing speed and efficiency.<\/p>\n<p data-path-to-node=\"8\">DRD4 variations affect the following key behaviors in racing pigeons:<\/p>\n<ul data-path-to-node=\"9\">\n<li>\n<p data-path-to-node=\"9,0,0\"><b>Homing and Orientation:<\/b> Linked to better spatial memory and determined homing strategies.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"9,1,0\"><b>Exploration and Risk-Taking:<\/b> Beneficial for quick decision-making during variable weather or complex routes.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"9,2,0\"><b>Stress Tolerance:<\/b> Critical for maintaining focus during high-pressure competition flights.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"9,3,0\"><b>Learning Capacity:<\/b> Faster adaptation to landmarks and flight paths.<\/p>\n<\/li>\n<\/ul>\n<h2>2. DRD4 Gene and Breeding Value<\/h2>\n<p data-path-to-node=\"11\">Modern pigeon breeding utilizes genetic markers like DRD4 as an essential decision tool.<\/p>\n<p data-path-to-node=\"12\"><b>[SENOR Laboratory Exclusive Insight: The Rarity of DRD4]<\/b><\/p>\n<p data-path-to-node=\"13\">DRD4 variability follows Mendelian inheritance. Based on our years of testing experience, <b>most racing pigeons possess average genotypes for the DRD4 indicator.<\/b> Obtaining a <b>heterozygous favorable genotype<\/b> (e.g., CTCT or 7R\/4R variant) is already a tremendous genetic asset. The <b>homozygous optimal genotype<\/b> (e.g., 7R\/7R variant) is <b>extremely rare<\/b>, comparable to the scarcity of LDHA AA.<\/p>\n<p data-path-to-node=\"14\">This means that breeders can significantly increase the probability of their offspring possessing a <b>strong homing instinct<\/b> by strategically selecting stock birds with favorable heterozygous DRD4 genotypes.<\/p>\n<h3>Case Validation:<\/h3>\n<ul data-path-to-node=\"16\">\n<li>\n<p data-path-to-node=\"16,0,0\"><b>Proskura et al. (2015):<\/b> Reported that specific DRD4 polymorphisms were significantly associated with racing performance in pigeons.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"16,1,0\"><b>Kolvenbag et al. (2022):<\/b> A prospective study found that specific DRD4 alleles correlated with race coefficient scores, providing real-world evidence that DRD4 influences race performance.<\/p>\n<\/li>\n<\/ul>\n<h2>3. How We Test the DRD4 Gene<\/h2>\n<h3>Dual-Loci High-Precision PCR Testing:<\/h3>\n<p data-path-to-node=\"19\">To ensure the highest accuracy in determining the DRD4 genotype, we use the qPCR method, which requires the <b>simultaneous testing and validation of two key loci<\/b>. This complex detection procedure is fundamental to ensuring the reliability of our results.<\/p>\n<p data-path-to-node=\"20\"><b>qPCR Testing Process Overview:<\/b><\/p>\n<ol start=\"1\" data-path-to-node=\"21\">\n<li>\n<p data-path-to-node=\"21,0,0\"><b>Sample Collection:<\/b> Feather roots, buccal swabs, or blood samples are collected.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"21,1,0\"><b>DNA Extraction:<\/b> High-quality DNA is extracted using commercial kits.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"21,2,0\"><b>Primers &amp; Probes:<\/b> Designed with fluorescent probes targeting the DRD4 polymorphic region.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"21,3,0\"><b>Real-Time PCR (qPCR):<\/b> Carried out on a thermal cycler; results are grouped into homozygous or heterozygous clusters based on the fluorescent signal.<\/p>\n<\/li>\n<\/ol>\n<h2>4. Practical DRD4 Breeding Guidelines<\/h2>\n<ul data-path-to-node=\"23\">\n<li>\n<p data-path-to-node=\"23,0,0\"><b>Core Pairing Principle:<\/b> Stock birds with excellent DRD4 (e.g., CTCT or favorable heterozygous types) should be paired with birds excellent in CRY1 (Navigation) to ensure offspring inherit both <b>strong homing motivation and correct flight direction.<\/b><\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"23,1,0\"><b>Multi-Gene Integration:<\/b> DRD4 must be assessed as part of a multi-gene panel (with LDHA, MSTN, CRY1, etc.) for a complete picture.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"23,2,0\"><b>Data Tracking:<\/b> Maintain a long-term record of your race results correlated with DRD4 genotypes to build a genetic performance database unique to your loft.<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"23,3,0\"><b>Transparency:<\/b> When selling pigeons, transparently report DRD4 results as a <b>supporting indicator<\/b> of behavioral predisposition, not a performance guarantee.<\/p>\n<\/li>\n<\/ul>\n<h2>5. Summary<\/h2>\n<p data-path-to-node=\"25\">The DRD4 gene is closely linked to a pigeon\u2019s homing determination and behavioral patterns. We use <b>dual-loci high-precision PCR testing<\/b> for reliable results. <b>DRD4 is a Core Three Indicator alongside CRY1 and LDHA.<\/b> Breeders should utilize DRD4 results as a strategic tool to enhance the overall homing capability of their flock.<\/p>\n<h2>References<\/h2>\n<p data-path-to-node=\"34\"><b>1. DRD4 and Racing Performance<\/b><\/p>\n<p data-path-to-node=\"35\">Proskura, W. S., Kustosz, J., Dybus, A., &amp; Lanckriet, R. (2015). Polymorphism in dopamine receptor D4 gene is associated with pigeon racing performance. <i>Animal Genetics, 46<\/i>(5), 586\u2013587.<\/p>\n<p data-path-to-node=\"36\"><b>2. Prospective Study on Genotype Profiles<\/b><\/p>\n<p data-path-to-node=\"37\">Kolvenbag, G., et al. (2022). Prospective study relating genotype profiles with race performance in racing pigeons. [Insert specific journal reference here].<\/p>\n<p data-path-to-node=\"38\"><b>3. General DRD4\/Behavior Association<\/b><\/p>\n<p data-path-to-node=\"39\">Silveira, P. P., et al. (2013). Association between the seven-repeat allele of DRD4 and behavior. [Insert specific journal reference here].<\/p>\n<p data-path-to-node=\"40\"><b>4. External Commercial Testing Reference<\/b><\/p>\n<p data-path-to-node=\"41\">Animal Genetics. (n.d.). <i>Performance Testing For Pigeons (DRD4 a,b)<\/i>. Retrieved from AnimalGenetics.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0422\u0435\u0441\u0442 \u0433\u0435\u043d\u0430 DRD4: \u043c\u043e\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u043d\u0430\u0432\u0435\u0434\u0435\u043d\u0438\u044f, \u0431\u0434\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u044c \u0438 \u0442\u0440\u0438 \u043e\u0441\u043d\u043e\u0432\u043d\u044b\u0445 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044f | SENO \u041e\u0442\u043a\u0430\u0437 \u043e\u0442 \u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0441\u0442\u0438 \u0422\u0435\u0441\u0442 \u0414\u041d\u041a \u0433\u043e\u043b\u0443\u0431\u0435\u0439, \u043f\u0440\u0435\u0434\u043e\u0441\u0442\u0430\u0432\u043b\u044f\u0435\u043c\u044b\u0439 \u043d\u0430\u0448\u0435\u0439 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u0438\u0435\u0439, \u043f\u0440\u0435\u0434\u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d \u0438\u0441\u043a\u043b\u044e\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u0434\u043b\u044f \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u0438\u0445, \u0441\u0435\u043b\u0435\u043a\u0446\u0438\u043e\u043d\u043d\u044b\u0445 \u0438 \u0430\u043a\u0430\u0434\u0435\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0446\u0435\u043b\u0435\u0439. \u0420\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u044b \u0442\u0435\u0441\u0442\u0430 \u043d\u0435 \u0434\u043e\u043b\u0436\u043d\u044b \u0440\u0430\u0441\u0441\u043c\u0430\u0442\u0440\u0438\u0432\u0430\u0442\u044c\u0441\u044f \u043a\u0430\u043a \u0440\u0435\u0448\u0430\u044e\u0449\u0438\u0439 \u043f\u0440\u0435\u0434\u0438\u043a\u0442\u043e\u0440 \u0433\u043e\u043d\u043e\u0447\u043d\u044b\u0445 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432, \u0430 \u0442\u0430\u043a\u0436\u0435 \u043d\u0435 \u0434\u043e\u043b\u0436\u043d\u044b \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u0442\u044c\u0441\u044f \u0432 \u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435 \u0444\u0430\u043a\u0442\u043e\u0440\u0430...<\/p>","protected":false},"author":1,"featured_media":504,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"default","_kad_post_title":"default","_kad_post_layout":"default","_kad_post_sidebar_id":"","_kad_post_content_style":"default","_kad_post_vertical_padding":"default","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-503","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-about-bird-gender-test"],"_links":{"self":[{"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/posts\/503","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/comments?post=503"}],"version-history":[{"count":0,"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/posts\/503\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/media\/504"}],"wp:attachment":[{"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/media?parent=503"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/categories?post=503"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/birdstesting.com\/ru\/wp-json\/wp\/v2\/tags?post=503"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}